水溶液聚合放大合成方法研究与实践

Study and practice of scale-up synthesis of aqueous solution polymerization

摘要:

针对目前国内外水溶液聚合从实验室小样合成条件与工业化生产条件存在很大差异，且仍没有简便可行的科学指导方法问题，本研究以固井降失水剂放大合成为例，根据降失水剂合成特点，在相似性放大原则上研选了合成工艺条件为主的放大基准，并以此建立了搅拌功率N p 放大模型，开发了适用于水溶液聚合放大合成方法。室内采用放大合成方法，通过AMPS类固井降失水剂2～10倍体积量放大实验，所得产物与实验室小试最佳产物转化率和120 ℃API失水量差距分别在5%和10 mL以内，分子量和红外测试结果也表明是同一产物；同时成功指导了50 L中试生产，其产品质量稳定，产品的物理性能及固井水泥浆应用性能测试结果与实验室小试一致。结果表明，放大合成方法能有效降低放大效应对放大合成的影响。

Abstract:

There is a great difference between the conditions of laboratory-scale synthesis of aqueous solution polymerizationand those of industrial production at home and abroad, and there is still no simple and feasible proper guidance method. Taking the scale-up synthesis of the water reducer for cementation as an example, and according to the characteristics of the synthesis of the water reducer, this study selects the scale-up criteria with the synthesis process conditions as the main part on the principle of similarity scale-up; hence, has set up a stirring power Np amplificationmodel, and develops the scale up synthesis method suitable for aqueous solution polymerization. The scale-up synthesis method was used in lab to test the AMPS water reducer by 2 to 10 times volume, and the resultingproducts showed that, compared with the small scale test, the differences in the best product conversion rate and the 120°C API water loss were 5% and 10mL respectively. The molecular weight and infrared test results indicated they are the same products. The method has also been successfully used to guide 50L pilot production with stable the product quality, and the physical properties and cementing slurry application test results of the product were consistent with the small test. The results show that the scale-up synthesis method can effectively reduce the influence of the scale-up effect on scale-up synthesis.